Intracellular responses to bacterial pore-forming toxins, development of new anthelmintics, Bt toxin resistance .
Molecular and genetic analysis of Drosophila neural development.
Embryonic stem cell fate; plant resistance to infectious disease.
Genetics of neuronal and epidermal morphogenesis in C. elegans.
Plant molecular and cell biology. Regulation of gene expression and protein targeting.
Plant molecular biology, control of gene expression and ion transport.
Molecular genetics of plant hormone action; the ubiquitin-proteasome pathway in plants.
Mechanisms regulating gene expression and cell differentiation during development. G. proteins and signal transduction mechanisms.
Nuclear transport in vitro; nuclear pore structure; nuclear assembly
Genetics and molecular biology of protein degradation in yeast.
Cell biology of morphogenesis. Molecular mechanisms of organ development in mice
Systems biology of circadian clocks in plants and mammals.
Cellular morphogenesis. Functional genomic analysis of cell shape changes in Drosophila development.
Developmental biology; molecular genetics of development in Dictyostelium
Cellular and molecular mechanisms underlying the specification of neuronal identity, growth cone motility and navigation, target selection and the generation of neuronal arbors.
Molecular genetics of early Drosophila embryogenesis.
Pattern formation and cell fate specification in Drosophila development.
Plant molecular biology, molecular mechanisms of tissue-specific gene expression in maize.
Plant cell and molecular biology, signal transduction and ion channels in higher plant cells.
Molecular genetic analysis of plant cell division and morphogenesis.
Vertebrate blood cell development, biology of hematopoietic stem and progenitor cells.
Investigating host/pathogen interactions in the roundworm C. elegans, including extracellular and intracellular pathogens.
Molecular genetic analysis of signal transduction in Drosophila development and immunity.
Wienhausen, Gabriele Senior Lecturer with Security of Employment
mRNA localization, translational control, and membrane trafficking in
Drosophila melanogaster.
Molecular and genetic analyses of fruit development.
Developmental genetics of organogenesis: regulation of heart size and shape in zeb
Plant Biology, Molecular mechanisms of auxin homeostasis and signal transduction.
Evolutionary processes in microbes: bacteria and their viruses.
Responses of plant communities and ecosystems to global environmental changes; restoration of native plant communities.
Ecological basis of invasive species. Argentine Ants, Fire Ants - California.
Plant population biology; mating system evolution; ecological genetics.
Speciation and adaptation to novel environments; Mating system evolution; Drosophila evolutionary genetics.
Evolution of animal language: symbolic communication in highly social bees; sensory physiology and mechanisms of multi-modal communication; bioacoustics; Cyborg bee project.
Physical and biotic controls on the distribution and diversity of species in benthic marine ecosystems.
Molecular evolution; genetic variation at DNA level.
Conservation and evolutionary biology; speciation; genetics of endangered species.
Environmental genomics; Microbial oceanography, ecology, evolution, biogeography; Genetic structure of microbial populations; Molecular genetics and ecological physiology.
Cryoelectron microscopy and three-dimensional, computer reconstruction of macromolecules
Biochemical genetics of circadian rhythms and mitochondrial membranes in Neurospora.
Mechanisms by which interferons and other cytokines activate the transcription of early response genes.
Evolution of protein structure and function.
Molecular Signaling in Stem Cells, Metabolic Disorders and Cancer
Biochemical and genetic approaches to the control of gene activity.
Interactions between microbial pathogens and hosts.
Generation and maintenance of T cell immunity.
Immune recognition and development.
Analysis of mechanisms of regulation of plasmid DNA replication and plasmid DNA partitioning.
Regulation of response to hypoxia and other microenvironmental stresses in vivo.
Mechanisms of pre-mRNA splicing; mRNA synthesis and processing
Transcription by RNA polymerase II.
Mechanisms of translation and mRNA turnover regulation in the control of eukaryotic gene expression.
Engineering algae for the production of therapeutic proteins and biofuels.
Mel, Stephanie Lecturer with Potential of Security of Employment
Helix-loop-helix proteins in B cell development and oncogenesis.
Protein crystallography
Regulation of functional homeostasis of the endoplasmic reticulum during the cell cycle progression.
Genetic and molecular approaches for understanding how tiny regulatory RNAs control gene expression.
Chromosome structure and function; genetics and epigenetics of transcription; position effects and transcriptional repression.
DNA segregation in prokaryotes.
How the progeny of a single cell division assume differing fates.
Analysis of protein structure and physiological function; post translational protein modification.
Transmembrane transport and the regulation of cellular physiology and transcription.
Somatic cell genetics. Molecular genetics of mammalian mitochondria.
Molecular biology; DNA replication and repair; computer applications to biology.
Organelle homeostasis; peroxisome function and biogenesis; peroxisomal disorders; peroxisomal protein import; peroxisome turnover by autophagy.
Lymphocyte development and signaling pathways in response to DNA damage.
Molecular mechanisms of cell differentiation and cancer development
Dendritic cells in innate and adaptive responses during viral infections.
Molecular and cellular neurobiology; regulation of synaptic components on neurons.
Butler, Madeline Lecturer with Security of Employment
Genetics of neuronal and epidermal morphogenesis in C. elegans.
French, Kathleen Lecturer with Security of Employment
Molecular neurobiology; mechanisms of cortical development and plasticity; calcium regulation of gene expression.
The Halpain Laboratory works at the interface of c ell biology and neuroscience to investigate molecular mechanisms in the mo rphogenesis of axons, dendrites, and synapses. Through time-lapse imaging and quantitative fluorescence-based analyses, we study how the actin and microtubule cytoskeletons regulate neuronal form and function.
Molecular genetic mechanisms of synapse formation, neuron circuit regulation and nerve regeneration.
Neurobiology; neuronal basis of behavior; development of simple nervous systems.
The Malinow Lab studies the biological basis of memory function and dysfunction by studying the physiology of rodent synapses.
Molecular neurobiology; molecular basis of electrical excitability and signal transduction in neural membranes; molecular design of channel proteins.
Neurobiology; the ubiquitin-proteasome system (UPS), one of the major cellular pathways controlling protein turnover in mammalian cells.
Neural coding of visual information by thalamic neurons; temporal and population coding, natural scenes, visual behavior.
Understanding the circuits controlling the spatial and temporal structure of cortical activity.
Neurobiology; computational models of the nervous system; mechanisms for synaptic plasticity.
Developmental neurobiology; control of expression of neuronal phenotypes
Systems neurobiology; representation and processing of olfactory information in simple olfactory system.
Molecular and cellular mechanisms of axon pathfinding, target specificaton and neuronal migration in nervous system development