Jacob Oppenheim·Jan 23, 2025The Map is not the TerritoryThere is no obligation for the laws governing the universe, or even a single biological process to be obvious, easily ascertainable, or…
Jacob Oppenheim·Oct 14, 2024Reflections on the 2024For most of us in biotech, John Hopfield is a name we might remember from grad school for work on enzymes. His theory of kinetic…
Jacob Oppenheim·Jul 1, 2024The Unreasonable Effectiveness of Design / Build / TestOver the past year, I’ve been collecting papers with surprising results about the success of machine learning in biology, ones that run…
Jacob Oppenheim·Mar 20, 2024Learning from Evolution: Why Protein Language Models WorkOver at the new OpenProtein.ai blog, Tristan Bepler and I wrote about the seemingly mysterious power of Deep Protein Language Models. Not…
Jacob Oppenheim·Mar 13, 2024Podcast: Data in BiotechRoss Katz from CorrDyn generously hosted me on the Data in Biotech podcast last week. Over the course of the conversation we discussed:
Jacob Oppenheim·Feb 2, 2024The World is not as Digitized as it SeemsConsider a handful of headlines from the two years:
Jacob Oppenheim·Oct 27, 2023Big Data:The social contract around big data and information technology is broken.
Jacob Oppenheim·Oct 6, 2023Big Data: A False PanaceaThe story goes that an angry father confronted Target employees after his daughter was mailed coupons for maternity products unnecessarily…
Jacob Oppenheim·Sep 22, 2023Software is Management TechnologyMy focus in writing over the past three months has been the interplay between powerful new computational methods, digital technologies, and…
Jacob Oppenheim·Aug 15, 2023The Age of Engineering BiologyI was on a panel about digitization and the data revolution at the annual Academy of Management meeting last weekend. My co-panelist and I…
