One of the most damaging myths about sexual assault isn't just the violence itself.โจIt's the question that so often follows: "Why didn't she fight back?" The answer is simple. Because the brain isn't a courtroom. It's a survival machine. When faced with overwhelming terror, many people don't fight. They don't flee. They freeze. Their amygdalaโthe brain's alarm systemโtakes over, shutting down higher reasoning and triggering an automatic survival response. It isn't weakness. It isn't consent. It isn't a conscious choice. It is biology. Yet far too many victims have had their credibility questioned because people expected Hollywood heroics instead of understanding human neuroscience. Imagine surviving one of the worst moments of your life... Only to have your trauma dismissed because your brain did exactly what evolution designed it to do. It's time we stop asking,โจ"Why didn't you do more?" And start asking,โจ"What happened to you?" Believing survivors doesn't mean abandoning due process. It means abandoning ignorance. Science has explained this for decades. Now it's our turn to educate ourselves and challenge the myths that continue to silence survivors. Source: Apple Tree Yard (BBC) La Gouvernance au Fรฉminin - Women in Governance #BelieveSurvivors #TraumaInformed #ViolenceAgainstWomen #EndVictimBlaming #GenderEquality #Neuroscience #StandWithWomen #Consent #Leadership #WomenInGovernance
Healthcare
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๐ฌ Latest pharma industry updates ๐ ๐ค Eli Lilly and Company and NVIDIA will build a 5-year AI research lab in the San Francisco Bay Area, investing $1B and using Nvidiaโs โVera Rubinโ AI chips. ๐ Eikon Therapeutics filed for an IPO after raising about $1.1B privately, it would be among the largest pre-IPO war chests since Moderna (2018). ๐ US pharma companies cut 25,367 jobs in 2025, far above 2024โs 14,010. ๐ผ Merck is reportedly negotiating to buy Revolution Medicines for about $30B; talks could conclude this month but remain uncertain. ๐งช Fabentech won approval for the 1st global ricin antidote, using equine-derived polyclonal antibodies. ๐ Lyra Therapeutics halted development of LYR-210 for chronic rhinosinusitis, cut most staff, and is exploring strategic options. ๐ Abivax spiked then cooled after reports Eli Lilly and Company might bid up to โฌ15B - Franceโs Economy Ministry said it received no foreign-investment authorization request and has no contact with Lilly. ๐ซ Atara Biotherapeutics received an FDA Complete Response Letter for EBVALLO, saying the single-arm ALLELE trial is insufficient for accelerated approval. ๐ฐ Kinaset Therapeutics raised $103M Series B to advance frevecitinib, an inhaled pan-JAK dry-powder therapy for severe uncontrolled asthma. ๐ง Insilico Medicineโs rentosertib is entering Phase 3 for idiopathic pulmonary fibrosis, potentially a first AI-origin drug to market. ๐ค Teva Pharmaceuticals and Royalty Pharma struck up to $500M financing for TEV-โ408, an antiโIL-15 antibody for vitiligo. ๐ง Novartis licensed Alzheimerโs antiโbeta-amyloid antibody programs from SciNeuro Pharmaceuticals for up to $1.7B.. ๐งฌ AbbVie will pay RemeGen $650M upfront (potentially >$5B total) for ex-China rights to a PD-1/VEGF bispecific antibody in Phase 1โ2 solid-tumor trials, including lung and breast cancer. ๐ค AstraZeneca acquired Modella AI (price undisclosed) to expand generative/agentic AI capabilities for oncology R&D. ๐งซ Caldera Therapeutics raised $112.5M (Series A/A1) for a Phase 1, aiming to raise efficacy ceilings in Crohnโs disease and ulcerative colitis. ๐๏ธ Sanofi is reportedly preparing a higher bid for Ocular Therapeutix, Inc. after its board rejected an initial $16/share (~$2.2B) offer. ๐ก๏ธ The FDA and EMA jointly published โgood practiceโ principles for using AI across the drug lifecycle. ๐๏ธ Novo Nordisk Foundation granted โฌ736M to Denmarkโs BioInnovation Institute (BII) through 2035, BII has incubated 130+ startups since 2018. ๐ American Cancer Society data show overall 5-year cancer survival reached 70%, up from ~50% around 1971. ๐ฉธ A Nature's Medicines study validated a finger-prick blood test for Alzheimerโs with 86% accuracy in 337 participants. ๐ท๏ธ TrumpRx is expected to launch soon in the US, connecting patients to manufacturers offering discounted prices on their own sites. ---------- ๐ฉ Get those updates directly via email (link in my profile)
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You should not need to spend money to land a job. If lack of transportation to interviews, job-related trainings, or even your first few weeks on the job is preventing you from being able to consider local opportunities, Lyft has a program that will offer you free rides. If you're anxious about interviewing because you don't have professional clothing, Dress for Success Worldwide (they have many local chapters), Career Gear, or your local Buy Nothing group may be able to help. There are also many similar organizations focused on a specific community so do a search for options in your area. If you need some coaching or support in your job search, you can connect with Never Search Alone or Pay Forward Coaching for support navigating your search. The US Dept of Labor has a site called CareerOneStop.org that has links to resources for many scenarios - jobseekers with criminal conviction, those combatting ageism, entry level workers, etc. They link to jobs, training, scholarship opportunities, and more. If you don't have a computer or phone that can handle video interviews, or a quiet space to take interviews, your local library will let you use their computers for this purpose. If you need childcare for your job search, most YMCA of the USA locations offer some form of drop off care while you use the facilities, and they often have quiet spaces for you to work from as well. Your local Boys & Girls Clubs of America may be able to help, and many communities have organizations (like Worksource or Working Connections) which can offer childcare subsidies while looking for work, enrolled in education programs, or starting a new job. And all of these resources are free!!
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Microsoft just released a 35-page report on medical AI - and itโs a reality check for healthcare. The paper, โThe Illusion of Readinessโ, tested six of the most popular models (OpenAI, Gemini, etc)โฆ across six multimodal medical benchmarks. And the verdict? The models scored high on medical exams. But theyโre not even close to being real-world ready. Hereโs what the stress tests revealed: โถ 1. Shortcut learning Models often answered correctly even when key information, like medical images, was removed. They werenโt reasoning - they were exploiting statistical shortcuts. That means benchmark wins may hide shallow understanding. โถ 2. Fragile under small changes Making small tweaks caused big swings in predictions. This fragility shows how unreliable model reasoning becomes under stress. In visual substitution tests, accuracy dropped from 83% to 52% when images were swapped - exposing shallow visualโanswer pairings. โถ 3. Fabricated reasoning Models produced confident, step-by-step medical explanations - but many were medically unsoundโฆ or entirely fabricated. Convincing to the eye, dangerous in practice. And more importantly, healthcare isnโt a multiple-choice exam. Itโs uncertainty, incomplete data, and high stakes. So Microsoftโs team calls for new standards: - Stress tests that expose fragility - Clinician-guided guidelines that profile benchmarks - Evaluation of robustness and trustworthiness - not just leaderboard scores The takeaway is simple: Medical AI may ace tests today. But until it proves reliable under stress, itโs not ready for the clinic. When do you think popular LLMs will be clinic-ready? #entrepreneurship #healthtech #AI
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๐ Imagine losing your sight for 10 yearsโฆ and then, the very first thing you do is recognize the faces of your loved ones again. Thatโs what happened to Jamal Furani, 78, thanks to a breakthrough in medical innovation: a fully synthetic cornea implant. No donor tissue. No immune rejection. A device that integrates directly with the eyeโs own tissue. ๐ก The deeper insight: The true revolution here isnโt only technological. Itโs structural. Today, corneal blindness affects millions worldwide, but most canโt be treated because there simply arenโt enough donor corneas. A synthetic cornea changes the equation. It turns a scarce resource (donations) into a potentially unlimited one (innovation). And hereโs what few realize: this implant doesnโt just restore vision. It restores autonomy, dignity, and human connection. Those are the โside effectsโ that make technology truly transformative. ๐ My take: The future of medicine wonโt just be about โhealing.โ It will be about reinventing our organs โ sometimes with solutions even better than the originals. If you could enhance or replace one organ with technology, which would you choose first? #Healthcare #Innovation #Biotech #FutureOfMedicine
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This 3D-scanned ear not only restores people's face, but their life in hours. The Epithese Ear is redefining whatโs possible in facial prosthetics. Every year, millions face the loss of an earโnot only with a huge physical impact, but also social burden. Now, a breakthrough in patient-specific prosthetics delivers what surgery alone couldnโt: Engineers and artisans built what medicine said couldnโt be done: โ An ear sculpted with 0.1mm 3D scanning โ 150 skin tones, seamlessly color-matched โ Secure integration with bone-anchored titanium โ Sculpted detail + texture, indistinguishable from life All from a studio that works more like a digital art lab than an operating room. The breakthrough? Immediate transformationโno waiting. From scan to new ear in less than 48 hours. Zero recovery, zero compromise. Why this changes everything: โ Speed when it matters most A new ear, fit perfectly, before your next meetingโreturn to daily life with confidence restored. โ Innovation, personalised โ Real Impact In patient outcomes: -97% ear symmetry* -Zero rejection rate -Full social reintegration Every year, 1.5 million people require facial prosthetics: -60% report social challenges -Countless avoid public interactions This changes the narrative. Human's artistry using 3D Design toolsโrestoring more than appearance, rebuilding lives. These advances show a bigger shift: hyper-personalized, non-invasive medical solutions that merge rapid digital fabrication with hands-on craftsmanship. Follow me, Dr. Martha Boeckenfeld for more breakthroughs transforming people's life. โป๏ธ Repost to share these life-changing innovations. #MedTech #FacialProsthetics #HealthInnovation #FutureOfMedicine
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India has 150 million+ people above the age 60 and there is a massive opportunity to keep them healthy & fit. But everyoneโs focused on Gen Z and no oneโs building for their parents. Itโs a hard business but a big one. Weโve invested in two companies. Hereโs why itโs tough and how one should crack it. Understand the reality first. 1. Elders donโt think of โhealthโ as proactive. Theyโre conditioned to wait until something breaks before acting. Youโre selling a solution to a problem they donโt know they have yet. 2. The 65-year-old needs it but their 35-year-old child pays for it. You're not selling to the elder. Youโre selling to their guilt-driven kids in Gurgaon or US. The buyer โ the user. 3. Trust is everything and you donโt have it. Indian elders trust: Their doctor, astrologer & their neighbour Not apps. Not tech bros. Not AI. You can't growth hack trust. You earn it slowly, locally. 4. They donโt want new habits. Theyโve had the same breakfast for 40 years. Youโre not selling a product. Youโre undoing decades of routine. 5. Distribution is hyperlocal. Elders donโt click Insta ads. They talk to the uncle in their colony. You scale building by building not by user cohorts. Yes, 150M+ elders. But itโs not one market. Itโs a thousand tiny tribes. Different languages, cultures, food habits, family structures, and tech comfort levels. If it were easy, Tata or Reliance wouldโve done it already. But itโs wide open now. The one who combines tech + trust + real care will win. So how do you crack it? 1. Think first principles & not trends Donโt build a โsenior fitness app.โ Ask: Why did they stop moving? What gives them joy? Youโre selling independence, not health. 2. Design for peace, not features. One-click help, One daily routine, One trusted face. Great elder products feel like human care not software. 3. Human-first, tech-enable. Donโt replace the daughter. Support her. Train 100 amazing elder coaches. Build tools to help them scale. 4. Don't focus on CAC. Here, itโs about trust per acquisition. Youโre not selling toothpaste. Youโre asking to be let into their daily life. Start offline. Build trust then tech. 5. Youโre in the business of habit change & not selling an app or a pill. Get them to walk 15 minutes a day. Add protein to breakfast. Laugh more. Sleep better. Small wins compound. Donโt build for scale first. Build for consistency. Be in the business of habit change. 6. This isnโt a hackable D2C play. Itโs a decade-long trust business. Build for one community. Get to know 100 elders by name. Solve deep, boring problems with elegance. Everyoneโs chasing the next billion youth users. But the hidden opportunity lies in serving the first 150 million elders. The elder care market in India isnโt just underserved. Itโs misunderstood and needs long-term play. Founders who crack this will build generational companies.
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Guide to Building an AI Agent 1๏ธโฃ ๐๐ต๐ผ๐ผ๐๐ฒ ๐๐ต๐ฒ ๐ฅ๐ถ๐ด๐ต๐ ๐๐๐ Not all LLMs are equal. Pick one that: - Excels in reasoning benchmarks - Supports chain-of-thought (CoT) prompting - Delivers consistent responses ๐ Tip: Experiment with models & fine-tune prompts to enhance reasoning. 2๏ธโฃ ๐๐ฒ๐ณ๐ถ๐ป๐ฒ ๐๐ต๐ฒ ๐๐ด๐ฒ๐ป๐โ๐ ๐๐ผ๐ป๐๐ฟ๐ผ๐น ๐๐ผ๐ด๐ถ๐ฐ Your agent needs a strategy: - Tool Use: Call tools when needed; otherwise, respond directly. - Basic Reflection: Generate, critique, and refine responses. - ReAct: Plan, execute, observe, and iterate. - Plan-then-Execute: Outline all steps first, then execute. ๐ Choosing the right approach improves reasoning & reliability. 3๏ธโฃ ๐๐ฒ๐ณ๐ถ๐ป๐ฒ ๐๐ผ๐ฟ๐ฒ ๐๐ป๐๐๐ฟ๐๐ฐ๐๐ถ๐ผ๐ป๐ & ๐๐ฒ๐ฎ๐๐๐ฟ๐ฒ๐ Set operational rules: - How to handle unclear queries? (Ask clarifying questions) - When to use external tools? - Formatting rules? (Markdown, JSON, etc.) - Interaction style? ๐ Clear system prompts shape agent behavior. 4๏ธโฃ ๐๐บ๐ฝ๐น๐ฒ๐บ๐ฒ๐ป๐ ๐ฎ ๐ ๐ฒ๐บ๐ผ๐ฟ๐ ๐ฆ๐๐ฟ๐ฎ๐๐ฒ๐ด๐ LLMs forget past interactions. Memory strategies: - Sliding Window: Retain recent turns, discard old ones. - Summarized Memory: Condense key points for recall. - Long-Term Memory: Store user preferences for personalization. ๐ Example: A financial AI recalls risk tolerance from past chats. 5๏ธโฃ ๐๐พ๐๐ถ๐ฝ ๐๐ต๐ฒ ๐๐ด๐ฒ๐ป๐ ๐๐ถ๐๐ต ๐ง๐ผ๐ผ๐น๐ & ๐๐ฃ๐๐ Extend capabilities with external tools: - Name: Clear, intuitive (e.g., "StockPriceRetriever") - Description: What does it do? - Schemas: Define input/output formats - Error Handling: How to manage failures? ๐ Example: A support AI retrieves order details via CRM API. 6๏ธโฃ ๐๐ฒ๐ณ๐ถ๐ป๐ฒ ๐๐ต๐ฒ ๐๐ด๐ฒ๐ป๐โ๐ ๐ฅ๐ผ๐น๐ฒ & ๐๐ฒ๐ ๐ง๐ฎ๐๐ธ๐ Narrowly defined agents perform better. Clarify: - Mission: (e.g., "I analyze datasets for insights.") - Key Tasks: (Summarizing, visualizing, analyzing) - Limitations: ("I donโt offer legal advice.") ๐ Example: A financial AI focuses on finance, not general knowledge. 7๏ธโฃ ๐๐ฎ๐ป๐ฑ๐น๐ถ๐ป๐ด ๐ฅ๐ฎ๐ ๐๐๐ ๐ข๐๐๐ฝ๐๐๐ Post-process responses for structure & accuracy: - Convert AI output to structured formats (JSON, tables) - Validate correctness before user delivery - Ensure correct tool execution ๐ Example: A financial AI converts extracted data into JSON. 8๏ธโฃ ๐ฆ๐ฐ๐ฎ๐น๐ถ๐ป๐ด ๐๐ผ ๐ ๐๐น๐๐ถ-๐๐ด๐ฒ๐ป๐ ๐ฆ๐๐๐๐ฒ๐บ๐ (๐๐ฑ๐๐ฎ๐ป๐ฐ๐ฒ๐ฑ) For complex workflows: - Info Sharing: What context is passed between agents? - Error Handling: What if one agent fails? - State Management: How to pause/resume tasks? ๐ Example: 1๏ธโฃ One agent fetches data 2๏ธโฃ Another summarizes 3๏ธโฃ A third generates a report Master the fundamentals, experiment, and refine and.. now go build something amazing! Happy agenting! ๐ค